Andrea Maier Wants to Solve Longevity's Evidence Problem

Dr. Andrea Maier realized a fundamental truth about herself when she was in medical school: She was fascinated by old age. As a child, she’d been awed by women of great age and power, like her grandmothers. Working with older patients, she was curious about the intricate cellular systems that either preserved or destroyed their bodies. “How can we maintain biology,” she asks now, “with the same care with which we might maintain a priceless work of art?”In 2025, Maier helped open a new clinical trial center at National University of Singapore, where she is director of the Academy for Healthy Longevity, which will enable teams to run multiple long-term trials assessing the effects of supplements, exercise routines, and other lifestyle interventions for health span. Her groundbreaking body of clinical research investigating whether the various drugs and interventions that make mice live better, longer—including supplements like nicotinamide mononucleotide (NMN) and alpha-ketoglutarate (AKG)—translate into people has brought her to the forefront of longevity medicine worldwide. Maier hopes the brand-new, state-of-the-art center will help generate the evidence needed to give longevity m...