At Least One in Four NFL Players May Have CTE

An alarming number of professional football players in the U.S. may someday have chronic traumatic encephalopathy (CTE), the neurodegenerative disease associated with repeated concussions and sub-concussive hits to the head, a new study suggests. The research, published in the BMJ, studied the brains of NFL players who died from 2016 to 2021 and found that one in four had CTE—a figure that is almost certainly an undercount, the researchers say. Depending on how they crunched the numbers, the CTE incidence rose as high as 91%. “The one in four figure is intentionally the most conservative estimate possible,” says lead author Dr. Daniel Daneshvar, chair of the department of physical medicine and rehabilitation at Mass General Brigham and associate professor at Harvard Medical School. “We know the true prevalence is higher than that.”It was in 1928 that pathologist Harrison Martland first described the condition now known as CTE in boxers experiencing what he called “punch drunk” syndrome. It was not until 2002 that the disease was first diagnosed in an NFL player, when neuropathologist Bennet I. Omalu examined the brain of Mike Webster, a former player for the Pittsburgh Steelers, an...