Why There's a Shortage of Chemotherapy Drugs

When cisplatin came on the market in 1978, it revolutionized cancer care. Carboplatin, a related chemotherapy drug with fewer side effects, soon followed in 1986. Together, these two drugs have saved countless lives and are prescribed for up to 20% of cancer patients to treat ovarian, bladder, breast, lung, and other types of cancer. “They're the backbone for treatments for a lot of different types of cancer,” says Dr. Jacob Reibel, a medical oncologist at Dartmouth Cancer Center.And yet, in recent years, when some hospital pharmacists have gone to source these chemo drugs for patients, they’ve had difficulty. They’ve had to call around, looking for some other facility that might have extra doses. Doctors, for their part, have had to have tough conversations with patients. If there’s no carboplatin or cisplatin to be had, patients might be given another, less-optimal chemotherapy. Or doctors might try spacing the doses out more than they usually would, trying to stretch the supply. Some fear that these shortages, which have been ongoing since 2023, might make cancer more deadly. In June, the U.S. Pharmacopeia, a nonprofit scientific group, released their latest report on drug short...